Pharmaceutical dissolution tester is an effective alternative method to study and evaluate in vivo medicine bioavailability in vitro, and is also an important means to ensure and measure whether the production process and quality of solid oral preparations are reasonable and stable. It replaces the previous disintegration time limit inspection with scientific and advanced measurement methods, thereby improving the scientificity of the medicine quality control method and ensuring the clinical efficacy.

Influencing factors when using medical dissolution tester:

1. The degassing degree of the medium, the liquid temperature, the instrument vibration, the stirring speed, the position of the sampling point, the filtration speed, the position of the medicine in the cup or the basket, etc.

2. Factors of the medicine itself, such as solubility, surface area, structure and crystal form.

3. Factors in preparation, such as dosage form, prescription, excipients, process, medicine interaction, surfactant, particle size and total area size after disintegration of preparation or release of main medicine.

Laboratory dissolution tester is one of the necessary equipment commonly used in chemical preparation and testing, and plays an extremely important role in medicine quality control and evaluation.